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MRI and CT contrast media extravasation: A systematic review

BACKGROUND: This systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk. METHODS: Data were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomograph...

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Autores principales: Heshmatzadeh Behzadi, Ashkan, Farooq, Zerwa, Newhouse, Jeffery H., Prince, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851722/
https://www.ncbi.nlm.nih.gov/pubmed/29489663
http://dx.doi.org/10.1097/MD.0000000000010055
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author Heshmatzadeh Behzadi, Ashkan
Farooq, Zerwa
Newhouse, Jeffery H.
Prince, Martin R.
author_facet Heshmatzadeh Behzadi, Ashkan
Farooq, Zerwa
Newhouse, Jeffery H.
Prince, Martin R.
author_sort Heshmatzadeh Behzadi, Ashkan
collection PubMed
description BACKGROUND: This systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk. METHODS: Data were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomography (CT) or magnetic resonance imaging (MRI). RESULTS: Extravasation rates were 0.045% for gadolinium-based contrast agents (GBCA) and nearly 6-fold higher, 0.26% for iodinated contrast agents. Factors associated with increased contrast media extravasations included: older age, female gender, using an existing intravenous (IV) instead of placing a new IV in radiology, in-patient status, use of automated power injection, high injection rates, catheter location, and failing to warm up the more viscous contrast media to body temperature. CONCLUSION: Contrast media extravasation is infrequent but nearly 6 times less frequent with GBCA for MRI compared with iodinated contrast used in CT.
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spelling pubmed-58517222018-03-21 MRI and CT contrast media extravasation: A systematic review Heshmatzadeh Behzadi, Ashkan Farooq, Zerwa Newhouse, Jeffery H. Prince, Martin R. Medicine (Baltimore) 6800 BACKGROUND: This systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk. METHODS: Data were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomography (CT) or magnetic resonance imaging (MRI). RESULTS: Extravasation rates were 0.045% for gadolinium-based contrast agents (GBCA) and nearly 6-fold higher, 0.26% for iodinated contrast agents. Factors associated with increased contrast media extravasations included: older age, female gender, using an existing intravenous (IV) instead of placing a new IV in radiology, in-patient status, use of automated power injection, high injection rates, catheter location, and failing to warm up the more viscous contrast media to body temperature. CONCLUSION: Contrast media extravasation is infrequent but nearly 6 times less frequent with GBCA for MRI compared with iodinated contrast used in CT. Wolters Kluwer Health 2018-03-02 /pmc/articles/PMC5851722/ /pubmed/29489663 http://dx.doi.org/10.1097/MD.0000000000010055 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 6800
Heshmatzadeh Behzadi, Ashkan
Farooq, Zerwa
Newhouse, Jeffery H.
Prince, Martin R.
MRI and CT contrast media extravasation: A systematic review
title MRI and CT contrast media extravasation: A systematic review
title_full MRI and CT contrast media extravasation: A systematic review
title_fullStr MRI and CT contrast media extravasation: A systematic review
title_full_unstemmed MRI and CT contrast media extravasation: A systematic review
title_short MRI and CT contrast media extravasation: A systematic review
title_sort mri and ct contrast media extravasation: a systematic review
topic 6800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851722/
https://www.ncbi.nlm.nih.gov/pubmed/29489663
http://dx.doi.org/10.1097/MD.0000000000010055
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