Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity

Botulinum neurotoxins (BoNTs) are among the most potent toxins known and are also used to treat an increasing number of medical disorders. There are seven well-established serotypes (BoNT/A-G), which all act as zinc-dependent endopeptidases targeting specific members of the SNARE proteins required f...

Descripción completa

Detalles Bibliográficos
Autores principales: Masuyer, Geoffrey, Zhang, Sicai, Barkho, Sulyman, Shen, Yi, Henriksson, Linda, Košenina, Sara, Dong, Min, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851995/
https://www.ncbi.nlm.nih.gov/pubmed/29540745
http://dx.doi.org/10.1038/s41598-018-22842-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851995/
https://www.ncbi.nlm.nih.gov/pubmed/29540745
http://dx.doi.org/10.1038/s41598-018-22842-4

Ejemplares similares