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Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation
The evolutionarily conserved adhesion G protein-coupled receptors (aGPCRs) play critical roles in biological processes as diverse as brain development, cell polarity and innate immune functions. A defining feature of aGPCRs is the GPCR autoproteolysis inducing (GAIN) domain capable of self-catalytic...
Autores principales: | Huang, Yi-Shu, Chiang, Nien-Yi, Chang, Gin-Wen, Lin, Hsi-Hsien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852045/ https://www.ncbi.nlm.nih.gov/pubmed/29540735 http://dx.doi.org/10.1038/s41598-018-22849-x |
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