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A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios
In an attempt to increase profits and sustainability in the swine industry, the gut microbiome has become a focus of much research. In this study, we performed a comparative analysis of the gut microbiome in the ileum, cecum, and colon of Duroc × (Landrace × Yorkshire) (DLY) pigs showing two extreme...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852056/ https://www.ncbi.nlm.nih.gov/pubmed/29540768 http://dx.doi.org/10.1038/s41598-018-22692-0 |
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author | Quan, Jianping Cai, Gengyuan Ye, Jian Yang, Ming Ding, Rongrong Wang, Xingwang Zheng, Enqin Fu, Disheng Li, Shaoyun Zhou, Shenping Liu, Dewu Yang, Jie Wu, Zhenfang |
author_facet | Quan, Jianping Cai, Gengyuan Ye, Jian Yang, Ming Ding, Rongrong Wang, Xingwang Zheng, Enqin Fu, Disheng Li, Shaoyun Zhou, Shenping Liu, Dewu Yang, Jie Wu, Zhenfang |
author_sort | Quan, Jianping |
collection | PubMed |
description | In an attempt to increase profits and sustainability in the swine industry, the gut microbiome has become a focus of much research. In this study, we performed a comparative analysis of the gut microbiome in the ileum, cecum, and colon of Duroc × (Landrace × Yorkshire) (DLY) pigs showing two extreme feed conversion ratios (FCRs) using 16S rRNA gene sequencing. The results revealed that the microbial community in the cecum and colon had significantly higher alpha diversity than the ileum. We further identified 11, 55, and 55 operational taxonomic units (OTUs) with significantly different relative abundances between the high and low FCR pigs among the three gut locations, respectively. These OTUs were mainly associated with bacteria that participate in the metabolism of dietary polysaccharides and proteins. We then identified two and nine metabolic pathways that were enriched in the cecum and colon of the high FCR pigs, respectively. The results suggested that the short chain fatty acids and indolic compounds produced by microbial fermentation might influence porcine feed efficiency. These results should improve our understanding of microbiota compositions in the different gut locations of commercial pigs and provide important insights into the effect of gut microbiota on porcine FCRs. |
format | Online Article Text |
id | pubmed-5852056 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-58520562018-03-21 A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios Quan, Jianping Cai, Gengyuan Ye, Jian Yang, Ming Ding, Rongrong Wang, Xingwang Zheng, Enqin Fu, Disheng Li, Shaoyun Zhou, Shenping Liu, Dewu Yang, Jie Wu, Zhenfang Sci Rep Article In an attempt to increase profits and sustainability in the swine industry, the gut microbiome has become a focus of much research. In this study, we performed a comparative analysis of the gut microbiome in the ileum, cecum, and colon of Duroc × (Landrace × Yorkshire) (DLY) pigs showing two extreme feed conversion ratios (FCRs) using 16S rRNA gene sequencing. The results revealed that the microbial community in the cecum and colon had significantly higher alpha diversity than the ileum. We further identified 11, 55, and 55 operational taxonomic units (OTUs) with significantly different relative abundances between the high and low FCR pigs among the three gut locations, respectively. These OTUs were mainly associated with bacteria that participate in the metabolism of dietary polysaccharides and proteins. We then identified two and nine metabolic pathways that were enriched in the cecum and colon of the high FCR pigs, respectively. The results suggested that the short chain fatty acids and indolic compounds produced by microbial fermentation might influence porcine feed efficiency. These results should improve our understanding of microbiota compositions in the different gut locations of commercial pigs and provide important insights into the effect of gut microbiota on porcine FCRs. Nature Publishing Group UK 2018-03-14 /pmc/articles/PMC5852056/ /pubmed/29540768 http://dx.doi.org/10.1038/s41598-018-22692-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Quan, Jianping Cai, Gengyuan Ye, Jian Yang, Ming Ding, Rongrong Wang, Xingwang Zheng, Enqin Fu, Disheng Li, Shaoyun Zhou, Shenping Liu, Dewu Yang, Jie Wu, Zhenfang A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
title | A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
title_full | A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
title_fullStr | A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
title_full_unstemmed | A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
title_short | A global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
title_sort | global comparison of the microbiome compositions of three gut locations in commercial pigs with extreme feed conversion ratios |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852056/ https://www.ncbi.nlm.nih.gov/pubmed/29540768 http://dx.doi.org/10.1038/s41598-018-22692-0 |
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