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Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum

Dopamine D2 receptors (D2Rs) in the nucleus accumbens (NAc) regulate motivated behavior, but the underlying neurobiological mechanisms remain unresolved. Here, we show that selective upregulation of D2Rs in the indirect pathway of the adult NAc enhances the willingness to work for food. Mechanistic...

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Detalles Bibliográficos
Autores principales:	Gallo, Eduardo F., Meszaros, Jozsef, Sherman, Jeremy D., Chohan, Muhammad O., Teboul, Eric, Choi, Claire S., Moore, Holly, Javitch, Jonathan A., Kellendonk, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852096/ https://www.ncbi.nlm.nih.gov/pubmed/29540712 http://dx.doi.org/10.1038/s41467-018-03272-2

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