IL-33/ST2 signalling and crosstalk with FcεRI and TLR4 is targeted by the parasitic worm product, ES-62

ES-62 is a secreted parasitic worm-derived immunomodulator that exhibits therapeutic potential in allergy by downregulating aberrant MyD88 signalling to normalise the inflammatory phenotype and mast cell responses. IL-33 plays an important role in driving mast cell responses and promoting type-2 all...

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Detalles Bibliográficos
Autores principales: Ball, Dimity H., Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852134/
https://www.ncbi.nlm.nih.gov/pubmed/29540770
http://dx.doi.org/10.1038/s41598-018-22716-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852134/
https://www.ncbi.nlm.nih.gov/pubmed/29540770
http://dx.doi.org/10.1038/s41598-018-22716-9

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