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(18)F-FPYBF-2, a new F-18-labelled amyloid imaging PET tracer: first experience in 61 volunteers and 55 patients with dementia

OBJECTIVE: Recently, we developed a benzofuran derivative for the imaging of β-amyloid plaques, 5-(5-(2-(2-(2-(18)F-fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)-N-methylpyridin-2-amine ((18)F-FPYBF-2) (Ono et al., J Med Chem 54:2971–9, 2011). The aim of this study was to assess the feasibility of (18...

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Detalles Bibliográficos
Autores principales: Higashi, Tatsuya, Nishii, Ryuichi, Kagawa, Shinya, Kishibe, Yoshihiko, Takahashi, Masaaki, Okina, Tomoko, Suzuki, Norio, Hasegawa, Hiroshi, Nagahama, Yasuhiro, Ishizu, Koichi, Oishi, Naoya, Kimura, Hiroyuki, Watanabe, Hiroyuki, Ono, Masahiro, Saji, Hideo, Yamauchi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852179/
https://www.ncbi.nlm.nih.gov/pubmed/29388083
http://dx.doi.org/10.1007/s12149-018-1236-1

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