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8-O-Acetyl Shanzhiside Methylester From Lamiophlomis Rotata Reduces Neuropathic Pain by Inhibiting the ERK/TNF-α Pathway in Spinal Astrocytes

Lamiophlomis rotata (L. rotata; Benth.) Kudo is an effective traditional herb in the clinical treatment of chronic pain syndromes in China. 8-O-acetyl shanzhiside methylester (8-OaS), a chief component in L. rotata, possesses potent immunosuppressive activities and favorable analgesic effects. This...

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Detalles Bibliográficos
Autores principales:	Zhang, Wei, Bai, Yang, Qiao, Yu, Wang, Jian, Li, Meng-Ying, Wang, Jing-Wen, Jia, Na, Chen, Tao, Li, Yun-Qing, Wen, Ai-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852333/ https://www.ncbi.nlm.nih.gov/pubmed/29568261 http://dx.doi.org/10.3389/fncel.2018.00054

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