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Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma

Glioblastoma is the most aggressive primary brain tumor in humans and is virtually incurable with conventional therapies. Chimeric antigen receptor (CAR) T cell therapy targeting the glioblastoma antigen EphA2 is an attractive approach to improve outcomes because EphA2 is expressed highly in gliobla...

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Detalles Bibliográficos
Autores principales:	Yi, Zhongzhen, Prinzing, Brooke L., Cao, Felicia, Gottschalk, Stephen, Krenciute, Giedre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852415/ https://www.ncbi.nlm.nih.gov/pubmed/29552579 http://dx.doi.org/10.1016/j.omtm.2018.01.009

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