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Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation

Bioresorbable scaffolds (BRS) were introduced in clinical practice to overcome the long-term limitations of newer-generation drug-eluting stents. Despite some initial promising results of the Absorb BRS, safety concerns have led to the discontinuation of the commercialization of this device. Several...

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Autores principales: Ortega-Paz, Luis, Brugaletta, Salvatore, Sabaté, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852443/
https://www.ncbi.nlm.nih.gov/pubmed/29415486
http://dx.doi.org/10.3390/jcm7020027
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author Ortega-Paz, Luis
Brugaletta, Salvatore
Sabaté, Manel
author_facet Ortega-Paz, Luis
Brugaletta, Salvatore
Sabaté, Manel
author_sort Ortega-Paz, Luis
collection PubMed
description Bioresorbable scaffolds (BRS) were introduced in clinical practice to overcome the long-term limitations of newer-generation drug-eluting stents. Despite some initial promising results of the Absorb BRS, safety concerns have led to the discontinuation of the commercialization of this device. Several retrospective studies have assessed the impact of the so-called Pre-dilation, Sizing and Post-dilation (PSP) technique concluding that an optimal PSP technique can improve clinical outcomes following BRS implantation. In this article, the definition of the PSP technique, and the current evidence of its impact on clinical outcomes are put in perspective. Additionality, the relationship between the PSP technique and the dual-antiplatelet therapy to prevent scaffold thrombosis is addressed. Finally, the future perspectives of BRS technology in clinical practice are commented.
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spelling pubmed-58524432018-03-19 Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation Ortega-Paz, Luis Brugaletta, Salvatore Sabaté, Manel J Clin Med Review Bioresorbable scaffolds (BRS) were introduced in clinical practice to overcome the long-term limitations of newer-generation drug-eluting stents. Despite some initial promising results of the Absorb BRS, safety concerns have led to the discontinuation of the commercialization of this device. Several retrospective studies have assessed the impact of the so-called Pre-dilation, Sizing and Post-dilation (PSP) technique concluding that an optimal PSP technique can improve clinical outcomes following BRS implantation. In this article, the definition of the PSP technique, and the current evidence of its impact on clinical outcomes are put in perspective. Additionality, the relationship between the PSP technique and the dual-antiplatelet therapy to prevent scaffold thrombosis is addressed. Finally, the future perspectives of BRS technology in clinical practice are commented. MDPI 2018-02-06 /pmc/articles/PMC5852443/ /pubmed/29415486 http://dx.doi.org/10.3390/jcm7020027 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ortega-Paz, Luis
Brugaletta, Salvatore
Sabaté, Manel
Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation
title Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation
title_full Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation
title_fullStr Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation
title_full_unstemmed Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation
title_short Impact of PSP Technique on Clinical Outcomes Following Bioresorbable Scaffolds Implantation
title_sort impact of psp technique on clinical outcomes following bioresorbable scaffolds implantation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852443/
https://www.ncbi.nlm.nih.gov/pubmed/29415486
http://dx.doi.org/10.3390/jcm7020027
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