A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents

Millions of patients in the United States use anticoagulation for a variety of indications, such as the prevention of stroke in those with atrial fibrillation (AF) and the treatment and prevention of venous thrombosis. For over six decades warfarin was the only available oral anticoagulant, but now...

Descripción completa

Detalles Bibliográficos
Autores principales: Joppa, Stephanie A., Salciccioli, Justin, Adamski, Jill, Patel, Salma, Wysokinski, Waldemar, McBane, Robert, Al-Saffar, Farah, Esser, Heidi, Shamoun, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852445/
https://www.ncbi.nlm.nih.gov/pubmed/29439477
http://dx.doi.org/10.3390/jcm7020029
_version_ 1783306573645348864
author Joppa, Stephanie A.
Salciccioli, Justin
Adamski, Jill
Patel, Salma
Wysokinski, Waldemar
McBane, Robert
Al-Saffar, Farah
Esser, Heidi
Shamoun, Fadi
author_facet Joppa, Stephanie A.
Salciccioli, Justin
Adamski, Jill
Patel, Salma
Wysokinski, Waldemar
McBane, Robert
Al-Saffar, Farah
Esser, Heidi
Shamoun, Fadi
author_sort Joppa, Stephanie A.
collection PubMed
description Millions of patients in the United States use anticoagulation for a variety of indications, such as the prevention of stroke in those with atrial fibrillation (AF) and the treatment and prevention of venous thrombosis. For over six decades warfarin was the only available oral anticoagulant, but now several DOACs are available and their use has become more prevalent in recent years. In spite of this increased use, many physicians remain reluctant to prescribe DOACs due to concerns about bleeding and reversibility.
format Online
Article
Text
id pubmed-5852445
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-58524452018-03-19 A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents Joppa, Stephanie A. Salciccioli, Justin Adamski, Jill Patel, Salma Wysokinski, Waldemar McBane, Robert Al-Saffar, Farah Esser, Heidi Shamoun, Fadi J Clin Med Review Millions of patients in the United States use anticoagulation for a variety of indications, such as the prevention of stroke in those with atrial fibrillation (AF) and the treatment and prevention of venous thrombosis. For over six decades warfarin was the only available oral anticoagulant, but now several DOACs are available and their use has become more prevalent in recent years. In spite of this increased use, many physicians remain reluctant to prescribe DOACs due to concerns about bleeding and reversibility. MDPI 2018-02-11 /pmc/articles/PMC5852445/ /pubmed/29439477 http://dx.doi.org/10.3390/jcm7020029 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Joppa, Stephanie A.
Salciccioli, Justin
Adamski, Jill
Patel, Salma
Wysokinski, Waldemar
McBane, Robert
Al-Saffar, Farah
Esser, Heidi
Shamoun, Fadi
A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_full A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_fullStr A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_full_unstemmed A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_short A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
title_sort practical review of the emerging direct anticoagulants, laboratory monitoring, and reversal agents
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852445/
https://www.ncbi.nlm.nih.gov/pubmed/29439477
http://dx.doi.org/10.3390/jcm7020029
work_keys_str_mv AT joppastephaniea apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT salcicciolijustin apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT adamskijill apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT patelsalma apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT wysokinskiwaldemar apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT mcbanerobert apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT alsaffarfarah apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT esserheidi apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT shamounfadi apracticalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT joppastephaniea practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT salcicciolijustin practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT adamskijill practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT patelsalma practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT wysokinskiwaldemar practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT mcbanerobert practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT alsaffarfarah practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT esserheidi practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents
AT shamounfadi practicalreviewoftheemergingdirectanticoagulantslaboratorymonitoringandreversalagents

Ejemplares similares