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Tetrodotoxin, a Candidate Drug for Nav1.1-Induced Mechanical Pain?
Tetrodotoxin (TTX), the mode of action of which has been known since the 1960s, is widely used in pharmacology as a specific inhibitor of voltage-gated sodium channels (Nav channels). This toxin has contributed to the characterization of the allosteric model of the Nav channel, and to discriminating...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852500/ https://www.ncbi.nlm.nih.gov/pubmed/29470418 http://dx.doi.org/10.3390/md16020072 |