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Increased passive stiffness promotes diastolic dysfunction despite improved Ca(2+) handling during left ventricular concentric hypertrophy

AIMS: Concentric hypertrophy following pressure-overload is linked to preserved systolic function but impaired diastolic function, and is an important substrate for heart failure with preserved ejection fraction. While increased passive stiffness of the myocardium is a suggested mechanism underlying...

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Detalles Bibliográficos
Autores principales:	Røe, Åsmund T., Aronsen, Jan Magnus, Skårdal, Kristine, Hamdani, Nazha, Linke, Wolfgang A., Danielsen, Håvard E., Sejersted, Ole M., Sjaastad, Ivar, Louch, William E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852536/ https://www.ncbi.nlm.nih.gov/pubmed/28472418 http://dx.doi.org/10.1093/cvr/cvx087

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