High-yielding continuous-flow synthesis of antimalarial drug hydroxychloroquine

Numerous synthetic methods for the continuous preparation of fine chemicals and active pharmaceutical ingredients (API’s) have been reported in recent years resulting in a dramatic improvement in process efficiencies. Herein we report a highly efficient continuous synthesis of the antimalarial drug...

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Detalles Bibliográficos
Autores principales: Yu, Eric, Mangunuru, Hari P R, Telang, Nakul S, Kong, Caleb J, Verghese, Jenson, Gilliland III, Stanley E, Ahmad, Saeed, Dominey, Raymond N, Gupton, B Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852550/
https://www.ncbi.nlm.nih.gov/pubmed/29623120
http://dx.doi.org/10.3762/bjoc.14.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852550/
https://www.ncbi.nlm.nih.gov/pubmed/29623120
http://dx.doi.org/10.3762/bjoc.14.45

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