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Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease
Vascular endothelial growth factor A (VEGF-A) is a prominent pro-angiogenic and pro-permeability factor in the kidney. Alternative splicing of the terminal exon of VEGF-A through the use of an alternative 3′ splice site gives rise to a functionally different family of isoforms, termed VEGF-A(xxx)b,...
Autores principales: | Stevens, Megan, Oltean, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852594/ https://www.ncbi.nlm.nih.gov/pubmed/29462869 http://dx.doi.org/10.3390/genes9020098 |
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