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Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease

Vascular endothelial growth factor A (VEGF-A) is a prominent pro-angiogenic and pro-permeability factor in the kidney. Alternative splicing of the terminal exon of VEGF-A through the use of an alternative 3′ splice site gives rise to a functionally different family of isoforms, termed VEGF-A(xxx)b,...

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Detalles Bibliográficos
Autores principales: Stevens, Megan, Oltean, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852594/
https://www.ncbi.nlm.nih.gov/pubmed/29462869
http://dx.doi.org/10.3390/genes9020098

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