HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry

The chromosomal passenger complex (CPC) is directed to centromeres during mitosis via binding to H3T3ph and Sgo1. Whether and how heterochromatin protein 1α (HP1α) influences CPC localisation and function during mitotic entry is less clear. Here, we alter HP1α dynamics by fusing it to a CENP‐B DNA‐b...

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Detalles Bibliográficos
Autores principales: Ruppert, Jan G, Samejima, Kumiko, Platani, Melpomeni, Molina, Oscar, Kimura, Hiroshi, Jeyaprakash, A Arockia, Ohta, Shinya, Earnshaw, William C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852645/
https://www.ncbi.nlm.nih.gov/pubmed/29467217
http://dx.doi.org/10.15252/embj.201797677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852645/
https://www.ncbi.nlm.nih.gov/pubmed/29467217
http://dx.doi.org/10.15252/embj.201797677

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