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Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia

Research conducted during the 1980s demonstrated Se deficiency in humans. Increased inclusion of selenium in animal feeds started from the year 2000 onwards. The aim of this study was to estimate the effects of selenium inclusion in animal feeds on human selenium status and dietary habits of the Ser...

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Autores principales: Pavlovic, Zoran, Miletic, Ivanka, Zekovic, Milica, Nikolic, Marina, Glibetic, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852801/
https://www.ncbi.nlm.nih.gov/pubmed/29462952
http://dx.doi.org/10.3390/nu10020225
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author Pavlovic, Zoran
Miletic, Ivanka
Zekovic, Milica
Nikolic, Marina
Glibetic, Maria
author_facet Pavlovic, Zoran
Miletic, Ivanka
Zekovic, Milica
Nikolic, Marina
Glibetic, Maria
author_sort Pavlovic, Zoran
collection PubMed
description Research conducted during the 1980s demonstrated Se deficiency in humans. Increased inclusion of selenium in animal feeds started from the year 2000 onwards. The aim of this study was to estimate the effects of selenium inclusion in animal feeds on human selenium status and dietary habits of the Serbian population related to food of animal origin. Plasma selenium concentration in healthy adult volunteers, including residents of one of the regions with the lowest (Eastern Serbia, n = 60) and of one of the regions with the highest Se serum levels reported in the past (Belgrade, n = 82), was determined by hydride generation atomic absorption spectrometry. Multivariate analysis was employed to determine the correlation between Se plasma levels and dietary intake data derived from food frequency questionnaires and laboratory tests. The mean plasma Se level of the participants was 84.3 ± 15.9 μg/L (range: 47.3–132.1 μg/L), while 46% of participants had plasma Se levels lower than 80 μg/L. Frequency of meat, egg, and fish consumption was significantly correlated with plasma selenium level (r = 0.437, p = 0.000). Selenium addition to animal feed in the quantity of 0.14 mg/kg contributed to the improvement of human plasma selenium levels by approximately 30 μg/L.
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spelling pubmed-58528012018-03-19 Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia Pavlovic, Zoran Miletic, Ivanka Zekovic, Milica Nikolic, Marina Glibetic, Maria Nutrients Article Research conducted during the 1980s demonstrated Se deficiency in humans. Increased inclusion of selenium in animal feeds started from the year 2000 onwards. The aim of this study was to estimate the effects of selenium inclusion in animal feeds on human selenium status and dietary habits of the Serbian population related to food of animal origin. Plasma selenium concentration in healthy adult volunteers, including residents of one of the regions with the lowest (Eastern Serbia, n = 60) and of one of the regions with the highest Se serum levels reported in the past (Belgrade, n = 82), was determined by hydride generation atomic absorption spectrometry. Multivariate analysis was employed to determine the correlation between Se plasma levels and dietary intake data derived from food frequency questionnaires and laboratory tests. The mean plasma Se level of the participants was 84.3 ± 15.9 μg/L (range: 47.3–132.1 μg/L), while 46% of participants had plasma Se levels lower than 80 μg/L. Frequency of meat, egg, and fish consumption was significantly correlated with plasma selenium level (r = 0.437, p = 0.000). Selenium addition to animal feed in the quantity of 0.14 mg/kg contributed to the improvement of human plasma selenium levels by approximately 30 μg/L. MDPI 2018-02-16 /pmc/articles/PMC5852801/ /pubmed/29462952 http://dx.doi.org/10.3390/nu10020225 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pavlovic, Zoran
Miletic, Ivanka
Zekovic, Milica
Nikolic, Marina
Glibetic, Maria
Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia
title Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia
title_full Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia
title_fullStr Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia
title_full_unstemmed Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia
title_short Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia
title_sort impact of selenium addition to animal feeds on human selenium status in serbia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852801/
https://www.ncbi.nlm.nih.gov/pubmed/29462952
http://dx.doi.org/10.3390/nu10020225
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