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Phosphorylation-dependent stabilization of MZF1 upregulates N-cadherin expression during protein kinase CK2-mediated epithelial-mesenchymal transition

Epithelial-mesenchymal transition (EMT) is a critical process in invasion and metastasis of cancer cells. E-cadherin to N-cadherin switching is considered a molecular hallmark of EMT. Recently, we reported that increased CK2 activity fully induces E-cadherin to N-cadherin switching, but the molecula...

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Detalles Bibliográficos
Autores principales: Ko, Hyeonseok, Kim, Seongrak, Yang, Kyungmi, Kim, Kunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852951/
https://www.ncbi.nlm.nih.gov/pubmed/29540671
http://dx.doi.org/10.1038/s41389-018-0035-9