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Specific features of l-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphate/metal transport

BACKGROUND: In the l-histidine (His) biosynthetic pathway of Escherichia coli, the first key enzyme, ATP-phosphoribosyltransferase (ATP-PRT, HisG), is subject to different types of inhibition. Eliminating the feedback inhibition of HisG by the His end product is an important step that enables the ov...

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Detalles Bibliográficos
Autores principales:	Malykh, Evgeniya A., Butov, Ivan A., Ravcheeva, Anna B., Krylov, Alexander A., Mashko, Sergey V., Stoynova, Nataliya V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852967/ https://www.ncbi.nlm.nih.gov/pubmed/29544475 http://dx.doi.org/10.1186/s12934-018-0890-2

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