Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization

BACKGROUND: Acute ischemic stroke (AIS) is the most common type of cerebrovascular disease and is a leading cause of disability and death worldwide. Recently, a study suggested that transformation of microglia from the pro-inflammatory M1 state to the anti-inflammatory and tissue-reparative M2 pheno...

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Detalles Bibliográficos
Autores principales: Jiang, Mei, Liu, Xinghui, Zhang, Denghai, Wang, Ying, Hu, Xiaoxia, Xu, Fengxia, Jin, Mingming, Cao, Fanfan, Xu, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853059/
https://www.ncbi.nlm.nih.gov/pubmed/29540209
http://dx.doi.org/10.1186/s12974-018-1124-6

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