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Loss of fragile histidine triad (Fhit) protein expression alters the translation of cancer-associated mRNAs
OBJECTIVES: In > 50% of cancers tumor development involves the early loss of Fhit (fragile histidine triad) protein expression, yet the mechanistic pathway(s) by which Fhit mediates its tumor suppressor functions are not fully understood. Earlier attempts to identify a Fhit-deficient gene express...
Autores principales: | Kiss, Daniel L., Baez, William D., Huebner, Kay, Bundschuh, Ralf, Schoenberg, Daniel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853088/ https://www.ncbi.nlm.nih.gov/pubmed/29540221 http://dx.doi.org/10.1186/s13104-018-3278-9 |
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