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Loss of fragile histidine triad (Fhit) protein expression alters the translation of cancer-associated mRNAs

OBJECTIVES: In > 50% of cancers tumor development involves the early loss of Fhit (fragile histidine triad) protein expression, yet the mechanistic pathway(s) by which Fhit mediates its tumor suppressor functions are not fully understood. Earlier attempts to identify a Fhit-deficient gene express...

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Detalles Bibliográficos
Autores principales: Kiss, Daniel L., Baez, William D., Huebner, Kay, Bundschuh, Ralf, Schoenberg, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853088/
https://www.ncbi.nlm.nih.gov/pubmed/29540221
http://dx.doi.org/10.1186/s13104-018-3278-9

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