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Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis

BACKGROUND: Organogenesis is crucial for proper organ formation during mammalian embryonic development. However, the similarities and shared features between different organs and the cellular heterogeneity during this process at single-cell resolution remain elusive. RESULTS: We perform single-cell...

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Detalles Bibliográficos
Autores principales: Dong, Ji, Hu, Yuqiong, Fan, Xiaoying, Wu, Xinglong, Mao, Yunuo, Hu, Boqiang, Guo, Hongshan, Wen, Lu, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853091/
https://www.ncbi.nlm.nih.gov/pubmed/29540203
http://dx.doi.org/10.1186/s13059-018-1416-2