Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity

BACKGROUND: Galactosylation of immunoglobulin G (IgG) is reduced in rheumatoid arthritis (RA) and assumed to correlate with inflammation and altered humoral immunity. IgG hypogalactosylation also increases with age. To investigate dependencies in more detail, we compared IgG hypogalactosylation betw...

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Detalles Bibliográficos
Autores principales: Schwedler, Christian, Häupl, Thomas, Kalus, Ulrich, Blanchard, Véronique, Burmester, Gerd-Rüdiger, Poddubnyy, Denis, Hoppe, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853146/
https://www.ncbi.nlm.nih.gov/pubmed/29540200
http://dx.doi.org/10.1186/s13075-018-1540-0

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