Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

BACKGROUND: The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and lack of identified shared properties. Here we consider promoter conservation and...

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Detalles Bibliográficos
Autores principales: Amaral, Paulo P., Leonardi, Tommaso, Han, Namshik, Viré, Emmanuelle, Gascoigne, Dennis K., Arias-Carrasco, Raúl, Büscher, Magdalena, Pandolfini, Luca, Zhang, Anda, Pluchino, Stefano, Maracaja-Coutinho, Vinicius, Nakaya, Helder I., Hemberg, Martin, Shiekhattar, Ramin, Enright, Anton J., Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853149/
https://www.ncbi.nlm.nih.gov/pubmed/29540241
http://dx.doi.org/10.1186/s13059-018-1405-5

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