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Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin–angiotensin systems

BACKGROUND: Hypertension may result from high-fat (HF) diet induced-obesity and overexposure to glucocorticoids in utero. Recent studies demonstrated the potent contribution of adipose tissue’s renin-angiotensin system (RAS) to systemic RAS, which plays a key role in regulating blood pressure (BP)....

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Detalles Bibliográficos
Autores principales:	Yu, Hong-Ren, Tain, You-Lin, Tiao, Mao-Meng, Chen, Chih-Cheng, Sheen, Jiunn-Ming, Lin, I-Chun, Li, Shih-Wen, Tsai, Ching-Chou, Lin, Yu-Ju, Hsieh, Kai-Sheng, Huang, Li-Tung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853160/ https://www.ncbi.nlm.nih.gov/pubmed/29540174 http://dx.doi.org/10.1186/s12944-018-0701-0

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