Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta

Cyclotides are ultra-stable, backbone-cyclized plant defence peptides that have attracted considerable interest in the pharmaceutical industry. This is due to their range of native bioactivities as well as their ability to stabilize other bioactive peptides within their framework. However, a hindran...

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Detalles Bibliográficos
Autores principales: Poon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J, Anderson, Marilyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853369/
https://www.ncbi.nlm.nih.gov/pubmed/29309615
http://dx.doi.org/10.1093/jxb/erx422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853369/
https://www.ncbi.nlm.nih.gov/pubmed/29309615
http://dx.doi.org/10.1093/jxb/erx422

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