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Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized With Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine

BACKGROUND: The impact of inactivated polio vaccines (IPVs) on intestinal mucosal immune responses to live poliovirus is poorly understood. METHODS: In a 2014 phase 2 clinical trial, Panamanian infants were immunized at 6, 10, and 14 weeks of age with bivalent oral polio vaccine (bOPV) and randomize...

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Detalles Bibliográficos
Autores principales: Brickley, Elizabeth B, Strauch, Carolyn B, Wieland-Alter, Wendy F, Connor, Ruth I, Lin, Shu, Weiner, Joshua A, Ackerman, Margaret E, Arita, Minetaro, Oberste, M Steven, Weldon, William C, Sáez-Llorens, Xavier, Bandyopadhyay, Ananda S, Wright, Peter F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853416/
https://www.ncbi.nlm.nih.gov/pubmed/29304199
http://dx.doi.org/10.1093/infdis/jix556