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Longitudinal evaluation of Tau‐P301L transgenic mice reveals no cognitive impairments at 17 months of age

INTRODUCTION: Tau is a microtubule‐associated binding protein implicated in neurodegenerative tauopathies, including frontotemporal dementia (FTD) and Alzheimer's disease (AD). These diseases result in the intracellular accumulation of hyperphosphorylated tau in the form of neurofibrillary tang...

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Detalles Bibliográficos
Autores principales:	Kent, Brianne A., Heath, Christopher J., Kim, Chi Hun, Ahrens, Rosemary, Fraser, Paul E., St George‐Hyslop, Peter, Bussey, Timothy J., Saksida, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853624/ https://www.ncbi.nlm.nih.gov/pubmed/29568692 http://dx.doi.org/10.1002/brb3.896

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