Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation

Mammalian oocytes possess fascinating unknown factors, which can reprogram terminally differentiated germ cells or somatic cells into totipotent embryos. Here, we demonstrate that oocyte-specific homeobox 1 (Obox1), an oocyte-specific factor, can markedly enhance the generation of induced pluripoten...

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Detalles Bibliográficos
Autores principales: Wu, Li, Wu, You, Peng, Bing, Hou, Zhenzhen, Dong, Yu, Chen, Kang, Guo, Mingyue, Li, Han, Chen, Xia, Kou, Xiaochen, Zhao, Yanhong, Bi, Yan, Wang, Yixuan, Wang, Hong, Le, Rongrong, Kang, Lan, Gao, Shaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853649/
https://www.ncbi.nlm.nih.gov/pubmed/29033306
http://dx.doi.org/10.1016/j.stemcr.2017.09.012

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