Age-Related Differences in Influenza B Infection by Lineage in a Community-Based Sentinel System, 2010–2011 to 2015–2016, Canada

Age-related differences in influenza B lineage detection were explored in the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) from 2010–2011 to 2015–2016. Whereas >80% of B(Victoria) cases were <40 years old, B(Yamagata) cases showed a bimodal age distribution with 2...

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Detalles Bibliográficos
Autores principales: Skowronski, Danuta M, Chambers, Catharine, De Serres, Gaston, Sabaiduc, Suzana, Winter, Anne-Luise, Dickinson, James A, Gubbay, Jonathan B, Fonseca, Kevin, Drews, Steven J, Charest, Hugues, Martineau, Christine, Krajden, Mel, Petric, Martin, Bastien, Nathalie, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853978/
https://www.ncbi.nlm.nih.gov/pubmed/28934439
http://dx.doi.org/10.1093/infdis/jix393
Descripción
Sumario:Age-related differences in influenza B lineage detection were explored in the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) from 2010–2011 to 2015–2016. Whereas >80% of B(Victoria) cases were <40 years old, B(Yamagata) cases showed a bimodal age distribution with 27% who were <20 years old and 61% who were 30–64 years old, but with a notable gap in cases between 20 and 29 years old (4%). Overall, the median age was 20 years lower for B(Victoria) vs B(Yamagata) cases (20 vs 40 years; P < .01). Additional phylodynamic and immuno-epidemiological research is needed to understand age-related variation in influenza B risk by lineage, with potential implications for prevention and control across the lifespan.

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