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Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Ca(v)1.1 converge at E18.5

In skeletal muscle the coordinated actions of two mechanically coupled Ca(2+) channels—the 1,4-dihydropyridine receptor (Ca(v)1.1) and the type 1 ryanodine receptor (RYR1)–underlie the molecular mechanism of rapid cytosolic [Ca(2+)] increase leading to contraction. While both [Ca(2+)](i) and contrac...

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Detalles Bibliográficos
Autores principales:	Filipova, Dilyana, Henry, Margit, Rotshteyn, Tamara, Brunn, Anna, Carstov, Mariana, Deckert, Martina, Hescheler, Jürgen, Sachinidis, Agapios, Pfitzer, Gabriele, Papadopoulos, Symeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854361/ https://www.ncbi.nlm.nih.gov/pubmed/29543863 http://dx.doi.org/10.1371/journal.pone.0194428

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