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TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities

Once considered a phenotypically monomorphic bacterium, there is a growing body of work demonstrating heterogeneity among Mycobacterium tuberculosis (Mtb) strains in clinically relevant characteristics, including virulence and response to antibiotics. However, the genetic and molecular basis for mos...

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Detalles Bibliográficos
Autores principales:	Carey, Allison F., Rock, Jeremy M., Krieger, Inna V., Chase, Michael R., Fernandez-Suarez, Marta, Gagneux, Sebastien, Sacchettini, James C., Ioerger, Thomas R., Fortune, Sarah M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854444/ https://www.ncbi.nlm.nih.gov/pubmed/29505613 http://dx.doi.org/10.1371/journal.ppat.1006939

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