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Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart

Research into gene therapy for heart failure has gained renewed interest as a result of improved safety and availability of adeno-associated viral vectors (AAV). While magnetic resonance imaging (MRI) is standard for functional assessment of gene therapy outcomes, quantitation of gene transfer/expre...

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Detalles Bibliográficos
Autores principales:	Meier, Shelby, Gilad, Assaf A., Brandon, J. Anthony, Qian, Chenghao, Gao, Erhe, Abisambra, Jose F., Vandsburger, Moriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854573/ https://www.ncbi.nlm.nih.gov/pubmed/29545551 http://dx.doi.org/10.1038/s41598-018-22993-4

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