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Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death
Excitotoxicity leads to the activation of a cytotoxic cascade that causes neuronal death. In the retina, retinal ganglion cells (RGCs) die after an excitotoxic insult. Multiple pathways have been proposed to contribute to RGC death after an excitotoxic insult, including TNF signaling, JNK activation...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854579/ https://www.ncbi.nlm.nih.gov/pubmed/29545615 http://dx.doi.org/10.1038/s41598-018-22848-y |