Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death

Excitotoxicity leads to the activation of a cytotoxic cascade that causes neuronal death. In the retina, retinal ganglion cells (RGCs) die after an excitotoxic insult. Multiple pathways have been proposed to contribute to RGC death after an excitotoxic insult, including TNF signaling, JNK activation...

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Detalles Bibliográficos
Autores principales: Fahrenthold, Berkeley K., Fernandes, Kimberly A., Libby, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854579/
https://www.ncbi.nlm.nih.gov/pubmed/29545615
http://dx.doi.org/10.1038/s41598-018-22848-y

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