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Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice
Pancreatic beta-cells are selectively destroyed by the host immune system in type 1 diabetes. Thus, drugs that preserve beta-cell mass and/or function have the potential to prevent or slow the progression of this disease. We recently reported that the use-dependent sodium channel blocker, carbamazep...
Autores principales: | Lee, Jason T. C., Shanina, Iryna, Chu, Yung Ning, Horwitz, Marc S., Johnson, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854601/ https://www.ncbi.nlm.nih.gov/pubmed/29545618 http://dx.doi.org/10.1038/s41598-018-23026-w |
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