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Functional analysis of the Drosophila RhoGAP Cv-c protein and its equivalence to the human DLC3 and DLC1 proteins

RhoGAP proteins control the precise regulation of the ubiquitous small RhoGTPases. The Drosophila Crossveinless-c (Cv-c) RhoGAP is homologous to the human tumour suppressor proteins Deleted in Liver Cancer 1–3 (DLC1-3) sharing an identical arrangement of SAM, GAP and START protein domains. Here we a...

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Detalles Bibliográficos
Autores principales:	Sotillos, Sol, Aguilar-Aragon, Mario, Hombría, James Castelli-Gair
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854602/ https://www.ncbi.nlm.nih.gov/pubmed/29545526 http://dx.doi.org/10.1038/s41598-018-22794-9

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