Sensitive and frequent identification of high avidity neo-epitope specific CD8(+) T cells in immunotherapy-naive ovarian cancer

Immunotherapy directed against private tumor neo-antigens derived from non-synonymous somatic mutations is a promising strategy of personalized cancer immunotherapy. However, feasibility in low mutational load tumor types remains unknown. Comprehensive and deep analysis of circulating and tumor-infi...

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Detalles Bibliográficos
Autores principales: Bobisse, Sara, Genolet, Raphael, Roberti, Annalisa, Tanyi, Janos L., Racle, Julien, Stevenson, Brian J., Iseli, Christian, Michel, Alexandra, Le Bitoux, Marie-Aude, Guillaume, Philippe, Schmidt, Julien, Bianchi, Valentina, Dangaj, Denarda, Fenwick, Craig, Derré, Laurent, Xenarios, Ioannis, Michielin, Olivier, Romero, Pedro, Monos, Dimitri S., Zoete, Vincent, Gfeller, David, Kandalaft, Lana E., Coukos, George, Harari, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854609/
https://www.ncbi.nlm.nih.gov/pubmed/29545564
http://dx.doi.org/10.1038/s41467-018-03301-0

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