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Neuromodulatory Correlates of Pupil Dilation

Pupillometry has long been used as a measure of brain state. Changes in pupil diameter are thought to coincide with the activity of neuromodulators, including noradrenaline and acetylcholine, producing alterations in the brain state and corresponding changes in behavior. Here we review mechanisms un...

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Detalles Bibliográficos
Autores principales: Larsen, Rylan S., Waters, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854659/
https://www.ncbi.nlm.nih.gov/pubmed/29593504
http://dx.doi.org/10.3389/fncir.2018.00021
Descripción
Sumario:Pupillometry has long been used as a measure of brain state. Changes in pupil diameter are thought to coincide with the activity of neuromodulators, including noradrenaline and acetylcholine, producing alterations in the brain state and corresponding changes in behavior. Here we review mechanisms underlying the control of pupil diameter and how these mechanisms are correlated with changes in cortical activity and the recruitment of neuromodulatory circuits.