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Single- and two-photon imaging of human micrometastases and disseminated tumour cells with conjugates of nanobodies and quantum dots
Early detection of malignant tumours and, especially, micrometastases and disseminated tumour cells is still a challenge. In order to implement highly sensitive diagnostic tools we demonstrate the use of nanoprobes engineered from nanobodies (single-domain antibodies, sdAbs) and fluorescent quantum...
Autores principales: | Ramos-Gomes, Fernanda, Bode, Julia, Sukhanova, Alyona, Bozrova, Svetlana V., Saccomano, Mara, Mitkovski, Miso, Krueger, Julia Eva, Wege, Anja K., Stuehmer, Walter, Samokhvalov, Pavel S., Baty, Daniel, Chames, Patrick, Nabiev, Igor, Alves, Frauke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854706/ https://www.ncbi.nlm.nih.gov/pubmed/29545609 http://dx.doi.org/10.1038/s41598-018-22973-8 |
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