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New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia

BACKGROUND: We sought to develop a novel index based on the skeletal muscle mass that reflects the change of quality of life (QOL), and is the most appropriate index for the body composition of the elderly in Korea. Whether lower extremity skeletal muscle mass index (LESMI) is an appropriate novel n...

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Autores principales: Moon, Jeong Jae, Park, Sam-Guk, Ryu, Seung Min, Park, Chan-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854819/
https://www.ncbi.nlm.nih.gov/pubmed/29564302
http://dx.doi.org/10.11005/jbm.2018.25.1.15
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author Moon, Jeong Jae
Park, Sam-Guk
Ryu, Seung Min
Park, Chan-Ho
author_facet Moon, Jeong Jae
Park, Sam-Guk
Ryu, Seung Min
Park, Chan-Ho
author_sort Moon, Jeong Jae
collection PubMed
description BACKGROUND: We sought to develop a novel index based on the skeletal muscle mass that reflects the change of quality of life (QOL), and is the most appropriate index for the body composition of the elderly in Korea. Whether lower extremity skeletal muscle mass index (LESMI) is an appropriate novel new index to diagnose patients with sarcopenia was also evaluated. A cut-off value for each index was reported to facilitate the diagnosis of patients with sarcopenia in a Korean population. METHODS: We used the 5th Korean National Health and Nutrition Examination Survey data from 2010. We analyzed 409 elderly patients, including 231 men and 178 women, aged ≥65 years. Patients were diagnosed by calculating their skeletal muscle index based on the skeletal muscle mass measured using dual energy X-ray absorptiometry. Obesity and osteoporosis were used to screen data and EuroQOL-5 dimension as a health questionnaire. RESULTS: The prevalence of sarcopenia in each index was obtained based on its cut-off value for diagnosing sarcopenia. There was a significant difference between the obesity rate of elderly patients diagnosed with sarcopenia and those who were not based on each index. There was no significant difference in the prevalence of osteoporosis between the groups. Sarcopenia diagnosis based on the LESMI was significantly correlated with QOL. CONCLUSIONS: LESMI, a novel index based on skeletal muscle mass, reflects changes in QOL and is appropriate for the body composition of elderly people in Korea.
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spelling pubmed-58548192018-03-21 New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia Moon, Jeong Jae Park, Sam-Guk Ryu, Seung Min Park, Chan-Ho J Bone Metab Original Article BACKGROUND: We sought to develop a novel index based on the skeletal muscle mass that reflects the change of quality of life (QOL), and is the most appropriate index for the body composition of the elderly in Korea. Whether lower extremity skeletal muscle mass index (LESMI) is an appropriate novel new index to diagnose patients with sarcopenia was also evaluated. A cut-off value for each index was reported to facilitate the diagnosis of patients with sarcopenia in a Korean population. METHODS: We used the 5th Korean National Health and Nutrition Examination Survey data from 2010. We analyzed 409 elderly patients, including 231 men and 178 women, aged ≥65 years. Patients were diagnosed by calculating their skeletal muscle index based on the skeletal muscle mass measured using dual energy X-ray absorptiometry. Obesity and osteoporosis were used to screen data and EuroQOL-5 dimension as a health questionnaire. RESULTS: The prevalence of sarcopenia in each index was obtained based on its cut-off value for diagnosing sarcopenia. There was a significant difference between the obesity rate of elderly patients diagnosed with sarcopenia and those who were not based on each index. There was no significant difference in the prevalence of osteoporosis between the groups. Sarcopenia diagnosis based on the LESMI was significantly correlated with QOL. CONCLUSIONS: LESMI, a novel index based on skeletal muscle mass, reflects changes in QOL and is appropriate for the body composition of elderly people in Korea. The Korean Society for Bone and Mineral Research 2018-02 2018-02-28 /pmc/articles/PMC5854819/ /pubmed/29564302 http://dx.doi.org/10.11005/jbm.2018.25.1.15 Text en Copyright © 2018 The Korean Society for Bone and Mineral Research http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moon, Jeong Jae
Park, Sam-Guk
Ryu, Seung Min
Park, Chan-Ho
New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia
title New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia
title_full New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia
title_fullStr New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia
title_full_unstemmed New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia
title_short New Skeletal Muscle Mass Index in Diagnosis of Sarcopenia
title_sort new skeletal muscle mass index in diagnosis of sarcopenia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854819/
https://www.ncbi.nlm.nih.gov/pubmed/29564302
http://dx.doi.org/10.11005/jbm.2018.25.1.15
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