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Lipid peroxidation regulates podocyte migration and cytoskeletal structure through redox sensitive RhoA signaling

Early podocyte loss is characteristic of chronic kidney diseases (CKD) in obesity and diabetes. Since treatments for hyperglycemia and hypertension do not prevent podocyte loss, there must be additional factors causing podocyte depletion. The role of oxidative stress has been implicated in CKD but i...

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Detalles Bibliográficos
Autores principales:	Kruger, Claudia, Burke, Susan J., Collier, J. Jason, Nguyen, Trang-Tiffany, Salbaum, J. Michael, Stadler, Krisztian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854917/ https://www.ncbi.nlm.nih.gov/pubmed/29547847 http://dx.doi.org/10.1016/j.redox.2018.02.024

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