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Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway

Hypertension-induced cardiac apoptosis is a major contributor to early-stage heart-failure. Our previous studies have found that p53-mediated mitochondrial fission is involved in aldosterone-induced podocyte apoptosis. However, it is not clear that whether p53-induced mitochondrial fission is critic...

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Detalles Bibliográficos
Autores principales:	Qi, Jia, Wang, Feng, Yang, Ping, Wang, Xuelian, Xu, Renjie, Chen, Jihui, Yuan, Yanggang, Lu, Zhaoyang, Duan, Junli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854948/ https://www.ncbi.nlm.nih.gov/pubmed/29593530 http://dx.doi.org/10.3389/fphar.2018.00176

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