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Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function
The axons of retinal ganglion cells (RGCs) are topographically sorted before they arrive at the optic tectum. This pre-target sorting, typical of axon tracts throughout the brain, is poorly understood. Here, we show that cytoplasmic FMR1-interacting proteins (CYFIPs) fulfill non-redundant functions...
Autores principales: | Cioni, Jean-Michel, Wong, Hovy Ho-Wai, Bressan, Dario, Kodama, Lay, Harris, William A., Holt, Christine E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855093/ https://www.ncbi.nlm.nih.gov/pubmed/29518358 http://dx.doi.org/10.1016/j.neuron.2018.01.027 |
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