Cargando…
Molecular Imprinting and Functional Polymers for All Transducers and Applications
The main challenge in developing a chemical sensor is the synthesis of recognition coatings, which are very sensitive and selective to analytes of interest. Molecular imprinting has proven to be the most innovative strategy for this purpose in functional polymer design in the last few decades. Moreo...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855119/ https://www.ncbi.nlm.nih.gov/pubmed/29364150 http://dx.doi.org/10.3390/s18020327 |
_version_ | 1783307033782517760 |
---|---|
author | Dickert, Franz L. |
author_facet | Dickert, Franz L. |
author_sort | Dickert, Franz L. |
collection | PubMed |
description | The main challenge in developing a chemical sensor is the synthesis of recognition coatings, which are very sensitive and selective to analytes of interest. Molecular imprinting has proven to be the most innovative strategy for this purpose in functional polymer design in the last few decades. Moreover, the introduction of functional groups brings about new applications for all available transducers. Sensitivity and selectivity features of sensor coatings can be tuned by this approach. The strategy produces molecular cavities and interaction sites in sensor coatings. The synthesis of these tailored recognition materials is performed in an outstanding manner, saving time and the high costs of chemicals. Furthermore, intermolecular interactions between the analyte and chemical layers will generate sites that are complementary to the analyte. This procedure can easily be done, directly on a transducer surface, which entails engulfing the analyte by a prepolymer and crosslinking the polymeric material. These imprinted polymers form a robust recognition layer on the transducer surface, which cannot be peeled off and can withstand very harsh conditions, both in gaseous and liquid media. These recognition materials are very suitable, for small molecules and even large bioparticles. |
format | Online Article Text |
id | pubmed-5855119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-58551192018-03-20 Molecular Imprinting and Functional Polymers for All Transducers and Applications Dickert, Franz L. Sensors (Basel) Editorial The main challenge in developing a chemical sensor is the synthesis of recognition coatings, which are very sensitive and selective to analytes of interest. Molecular imprinting has proven to be the most innovative strategy for this purpose in functional polymer design in the last few decades. Moreover, the introduction of functional groups brings about new applications for all available transducers. Sensitivity and selectivity features of sensor coatings can be tuned by this approach. The strategy produces molecular cavities and interaction sites in sensor coatings. The synthesis of these tailored recognition materials is performed in an outstanding manner, saving time and the high costs of chemicals. Furthermore, intermolecular interactions between the analyte and chemical layers will generate sites that are complementary to the analyte. This procedure can easily be done, directly on a transducer surface, which entails engulfing the analyte by a prepolymer and crosslinking the polymeric material. These imprinted polymers form a robust recognition layer on the transducer surface, which cannot be peeled off and can withstand very harsh conditions, both in gaseous and liquid media. These recognition materials are very suitable, for small molecules and even large bioparticles. MDPI 2018-01-24 /pmc/articles/PMC5855119/ /pubmed/29364150 http://dx.doi.org/10.3390/s18020327 Text en © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Editorial Dickert, Franz L. Molecular Imprinting and Functional Polymers for All Transducers and Applications |
title | Molecular Imprinting and Functional Polymers for All Transducers and Applications |
title_full | Molecular Imprinting and Functional Polymers for All Transducers and Applications |
title_fullStr | Molecular Imprinting and Functional Polymers for All Transducers and Applications |
title_full_unstemmed | Molecular Imprinting and Functional Polymers for All Transducers and Applications |
title_short | Molecular Imprinting and Functional Polymers for All Transducers and Applications |
title_sort | molecular imprinting and functional polymers for all transducers and applications |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855119/ https://www.ncbi.nlm.nih.gov/pubmed/29364150 http://dx.doi.org/10.3390/s18020327 |
work_keys_str_mv | AT dickertfranzl molecularimprintingandfunctionalpolymersforalltransducersandapplications |