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Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol

INTRODUCTION: Clubfoot is a common congenital birth defect, with an average prevalence of approximately 1 per 1000 live births, although this rate is reported to vary among different countries around the world. If it remains untreated, clubfoot causes permanent disability, limits educational and emp...

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Autores principales: Ansar, Adnan, Rahman, Ahmed Ehsanur, Romero, Lorena, Haider, Mohammad Rifat, Rahman, Mohammad Masudur, Moinuddin, Md, Siddique, Md Abu Bakkar, Mamun, Md Al, Mazumder, Tapas, Pirani, Shafique Pyarali, Mathias, Richard Gordon, Arifeen, Shams EI, Hoque, Dewan Md Emdadul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855200/
https://www.ncbi.nlm.nih.gov/pubmed/29511012
http://dx.doi.org/10.1136/bmjopen-2017-019246
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author Ansar, Adnan
Rahman, Ahmed Ehsanur
Romero, Lorena
Haider, Mohammad Rifat
Rahman, Mohammad Masudur
Moinuddin, Md
Siddique, Md Abu Bakkar
Mamun, Md Al
Mazumder, Tapas
Pirani, Shafique Pyarali
Mathias, Richard Gordon
Arifeen, Shams EI
Hoque, Dewan Md Emdadul
author_facet Ansar, Adnan
Rahman, Ahmed Ehsanur
Romero, Lorena
Haider, Mohammad Rifat
Rahman, Mohammad Masudur
Moinuddin, Md
Siddique, Md Abu Bakkar
Mamun, Md Al
Mazumder, Tapas
Pirani, Shafique Pyarali
Mathias, Richard Gordon
Arifeen, Shams EI
Hoque, Dewan Md Emdadul
author_sort Ansar, Adnan
collection PubMed
description INTRODUCTION: Clubfoot is a common congenital birth defect, with an average prevalence of approximately 1 per 1000 live births, although this rate is reported to vary among different countries around the world. If it remains untreated, clubfoot causes permanent disability, limits educational and employment opportunities, and personal growth. The aim of this systematic review and meta-analysis is to estimate the global birth prevalence of congenital clubfoot. METHODS AND ANALYSIS: Electronic databases including MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, Global Health, Latin American & Caribben Health Science Literature (LILACS), Maternity and Infant Care, Web of Science, Scopus and Google Scholar will be searched for observational studies based on predefined criteria and only in English language from inception of database in 1946 to 10 November 2017. A standard data extraction form will be used to extract relevant information from included studies. The Joanna Briggs Institute appraisal checklist will be used to assess the overall quality of studies reporting prevalence. All included studies will be assessed for risk of bias using a tool developed specifically for prevalence studies. Forest plots will be created to understand the overall random effects of pooled estimates with 95% CIs. An I(2) test will be done for heterogeneity of the results (P>0.05), and to identify the source of heterogeneity across studies, subgroup or meta-regression will be used to assess the contribution of each variable to the overall heterogeneity. A funnel plot will be used to identify reporting bias, and sensitivity analysis will be used to assess the impact of methodological quality, study design, sample size and the impact of missing data. ETHICS AND DISSEMINATION: This review will be conducted completely based on published data, so approval from an ethics committee or written consent will not be required. The results will be disseminated through a peer-reviewed publication and relevant conference presentations. PROSPERO REGISTRATION NUMBER: CRD42016041922.
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spelling pubmed-58552002018-03-19 Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol Ansar, Adnan Rahman, Ahmed Ehsanur Romero, Lorena Haider, Mohammad Rifat Rahman, Mohammad Masudur Moinuddin, Md Siddique, Md Abu Bakkar Mamun, Md Al Mazumder, Tapas Pirani, Shafique Pyarali Mathias, Richard Gordon Arifeen, Shams EI Hoque, Dewan Md Emdadul BMJ Open Public Health INTRODUCTION: Clubfoot is a common congenital birth defect, with an average prevalence of approximately 1 per 1000 live births, although this rate is reported to vary among different countries around the world. If it remains untreated, clubfoot causes permanent disability, limits educational and employment opportunities, and personal growth. The aim of this systematic review and meta-analysis is to estimate the global birth prevalence of congenital clubfoot. METHODS AND ANALYSIS: Electronic databases including MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, Global Health, Latin American & Caribben Health Science Literature (LILACS), Maternity and Infant Care, Web of Science, Scopus and Google Scholar will be searched for observational studies based on predefined criteria and only in English language from inception of database in 1946 to 10 November 2017. A standard data extraction form will be used to extract relevant information from included studies. The Joanna Briggs Institute appraisal checklist will be used to assess the overall quality of studies reporting prevalence. All included studies will be assessed for risk of bias using a tool developed specifically for prevalence studies. Forest plots will be created to understand the overall random effects of pooled estimates with 95% CIs. An I(2) test will be done for heterogeneity of the results (P>0.05), and to identify the source of heterogeneity across studies, subgroup or meta-regression will be used to assess the contribution of each variable to the overall heterogeneity. A funnel plot will be used to identify reporting bias, and sensitivity analysis will be used to assess the impact of methodological quality, study design, sample size and the impact of missing data. ETHICS AND DISSEMINATION: This review will be conducted completely based on published data, so approval from an ethics committee or written consent will not be required. The results will be disseminated through a peer-reviewed publication and relevant conference presentations. PROSPERO REGISTRATION NUMBER: CRD42016041922. BMJ Publishing Group 2018-03-06 /pmc/articles/PMC5855200/ /pubmed/29511012 http://dx.doi.org/10.1136/bmjopen-2017-019246 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Public Health
Ansar, Adnan
Rahman, Ahmed Ehsanur
Romero, Lorena
Haider, Mohammad Rifat
Rahman, Mohammad Masudur
Moinuddin, Md
Siddique, Md Abu Bakkar
Mamun, Md Al
Mazumder, Tapas
Pirani, Shafique Pyarali
Mathias, Richard Gordon
Arifeen, Shams EI
Hoque, Dewan Md Emdadul
Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
title Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
title_full Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
title_fullStr Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
title_full_unstemmed Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
title_short Systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
title_sort systematic review and meta-analysis of global birth prevalence of clubfoot: a study protocol
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855200/
https://www.ncbi.nlm.nih.gov/pubmed/29511012
http://dx.doi.org/10.1136/bmjopen-2017-019246
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