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Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study

OBJECTIVE: We aim to determine the incidence of delirium and describe its impacts on hospital length of stay (LOS) among non-delirious community-dwelling older adults with an 8-hour exposure to the emergency department (ED) environment. DESIGN: This is a prospective observational multicentre cohort...

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Autores principales: Émond, Marcel, Boucher, Valérie, Carmichael, Pierre-Hugues, Voyer, Philippe, Pelletier, Mathieu, Gouin, Émilie, Daoust, Raoul, Berthelot, Simon, Lamontagne, Marie-Eve, Morin, Michèle, Lemire, Stéphane, Minh Vu, Thien Tuong, Nadeau, Alexandra, Rheault, Marcel, Juneau, Lucille, Le Sage, Natalie, Lee, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855334/
https://www.ncbi.nlm.nih.gov/pubmed/29523559
http://dx.doi.org/10.1136/bmjopen-2017-018190
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author Émond, Marcel
Boucher, Valérie
Carmichael, Pierre-Hugues
Voyer, Philippe
Pelletier, Mathieu
Gouin, Émilie
Daoust, Raoul
Berthelot, Simon
Lamontagne, Marie-Eve
Morin, Michèle
Lemire, Stéphane
Minh Vu, Thien Tuong
Nadeau, Alexandra
Rheault, Marcel
Juneau, Lucille
Le Sage, Natalie
Lee, Jacques
author_facet Émond, Marcel
Boucher, Valérie
Carmichael, Pierre-Hugues
Voyer, Philippe
Pelletier, Mathieu
Gouin, Émilie
Daoust, Raoul
Berthelot, Simon
Lamontagne, Marie-Eve
Morin, Michèle
Lemire, Stéphane
Minh Vu, Thien Tuong
Nadeau, Alexandra
Rheault, Marcel
Juneau, Lucille
Le Sage, Natalie
Lee, Jacques
author_sort Émond, Marcel
collection PubMed
description OBJECTIVE: We aim to determine the incidence of delirium and describe its impacts on hospital length of stay (LOS) among non-delirious community-dwelling older adults with an 8-hour exposure to the emergency department (ED) environment. DESIGN: This is a prospective observational multicentre cohort study (March–July 2015). Patients were assessed two times per day during their entire ED stay and up to 24 hours on hospital ward. SETTING: The study took place in four Canadian EDs. PARTICIPANTS: 338 included patients: (1) aged ≥65 years; (2) who had an ED stay ≥8 hours; (3) were admitted to hospital ward and (4) were independent/semi-independent. MAIN OUTCOME(S) AND MEASURE(S): The primary outcomes of this study were incident delirium in the ED or within 24 hours of ward admission and ED and hospital LOS. Functional and cognitive status were assessed using validated Older Americans Resources and Services and the modified Telephone Interview for Cognitive Status tools. The Confusion Assessment Method was used to detect incident delirium. Univariate and multivariate analyses were conducted to evaluate outcomes. RESULTS: Mean age was 76.8 (±8.1), 17.7% were aged >85 years old and 48.8% were men. The mean incidence of delirium was 12.1% (n=41). Median IQR ED LOS was 32.4 (24.5–47.9) hours and hospital LOS was 146.6 (75.2–267.8) hours. Adjusted mean hospital LOS was increased by 105.4 hours (4.4 days) (95% CI 25.1 to 162.0, P<0.001) for patients who developed an episode of delirium compared with non-delirious patient. CONCLUSIONS: An incident delirium was observed in one of eight independent/semi-independent older adults after an 8-hour ED exposure. An episode of delirium increases hospital LOS by 4 days and therefore has important implications for patients and could contribute to ED overcrowding through a deleterious feedback loop.
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spelling pubmed-58553342018-03-19 Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study Émond, Marcel Boucher, Valérie Carmichael, Pierre-Hugues Voyer, Philippe Pelletier, Mathieu Gouin, Émilie Daoust, Raoul Berthelot, Simon Lamontagne, Marie-Eve Morin, Michèle Lemire, Stéphane Minh Vu, Thien Tuong Nadeau, Alexandra Rheault, Marcel Juneau, Lucille Le Sage, Natalie Lee, Jacques BMJ Open Emergency Medicine OBJECTIVE: We aim to determine the incidence of delirium and describe its impacts on hospital length of stay (LOS) among non-delirious community-dwelling older adults with an 8-hour exposure to the emergency department (ED) environment. DESIGN: This is a prospective observational multicentre cohort study (March–July 2015). Patients were assessed two times per day during their entire ED stay and up to 24 hours on hospital ward. SETTING: The study took place in four Canadian EDs. PARTICIPANTS: 338 included patients: (1) aged ≥65 years; (2) who had an ED stay ≥8 hours; (3) were admitted to hospital ward and (4) were independent/semi-independent. MAIN OUTCOME(S) AND MEASURE(S): The primary outcomes of this study were incident delirium in the ED or within 24 hours of ward admission and ED and hospital LOS. Functional and cognitive status were assessed using validated Older Americans Resources and Services and the modified Telephone Interview for Cognitive Status tools. The Confusion Assessment Method was used to detect incident delirium. Univariate and multivariate analyses were conducted to evaluate outcomes. RESULTS: Mean age was 76.8 (±8.1), 17.7% were aged >85 years old and 48.8% were men. The mean incidence of delirium was 12.1% (n=41). Median IQR ED LOS was 32.4 (24.5–47.9) hours and hospital LOS was 146.6 (75.2–267.8) hours. Adjusted mean hospital LOS was increased by 105.4 hours (4.4 days) (95% CI 25.1 to 162.0, P<0.001) for patients who developed an episode of delirium compared with non-delirious patient. CONCLUSIONS: An incident delirium was observed in one of eight independent/semi-independent older adults after an 8-hour ED exposure. An episode of delirium increases hospital LOS by 4 days and therefore has important implications for patients and could contribute to ED overcrowding through a deleterious feedback loop. BMJ Publishing Group 2018-03-08 /pmc/articles/PMC5855334/ /pubmed/29523559 http://dx.doi.org/10.1136/bmjopen-2017-018190 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Emergency Medicine
Émond, Marcel
Boucher, Valérie
Carmichael, Pierre-Hugues
Voyer, Philippe
Pelletier, Mathieu
Gouin, Émilie
Daoust, Raoul
Berthelot, Simon
Lamontagne, Marie-Eve
Morin, Michèle
Lemire, Stéphane
Minh Vu, Thien Tuong
Nadeau, Alexandra
Rheault, Marcel
Juneau, Lucille
Le Sage, Natalie
Lee, Jacques
Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
title Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
title_full Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
title_fullStr Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
title_full_unstemmed Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
title_short Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
title_sort incidence of delirium in the canadian emergency department and its consequences on hospital length of stay: a prospective observational multicentre cohort study
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855334/
https://www.ncbi.nlm.nih.gov/pubmed/29523559
http://dx.doi.org/10.1136/bmjopen-2017-018190
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