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Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells

The maintenance of ordinal cell cycle phases is a critical biological process in cancer genesis, which is a crucial target for anti-cancer drugs. As an important natural isoquinoline alkaloid from Chinese herbal medicine, Berberine (BBR) has been reported to possess anti-cancer potentiality to induc...

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Detalles Bibliográficos
Autores principales: Li, Fanni, Dong, Xiwen, Lin, Peng, Jiang, Jianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855549/
https://www.ncbi.nlm.nih.gov/pubmed/29360760
http://dx.doi.org/10.3390/ijms19020327

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