Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein

α-Synuclein (αS) is an intrinsically disordered protein that is associated with Parkinson’s disease (PD) through its ability to self-assemble into oligomers and fibrils. Inhibition of this oligomerization cascade is an interesting approach to developing therapeutical strategies and β-synuclein (βS)...

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Detalles Bibliográficos
Autores principales: Leitao, Andre, Bhumkar, Akshay, Hunter, Dominic J. B., Gambin, Yann, Sierecki, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855556/
https://www.ncbi.nlm.nih.gov/pubmed/29364143
http://dx.doi.org/10.3390/ijms19020334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855556/
https://www.ncbi.nlm.nih.gov/pubmed/29364143
http://dx.doi.org/10.3390/ijms19020334

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