Cargando…

Mesenchymal Stem Cells: Cell Fate Decision to Osteoblast or Adipocyte and Application in Osteoporosis Treatment

Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and degraded bone microstructure, which leads to increased bone fragility and risks of bone fracture. Osteoporosis is generally age related and has become a major disease of the world. Uncovering the molecular mechan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Lifang, Yin, Chong, Zhao, Fan, Ali, Arshad, Ma, Jianhua, Qian, Airong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855582/ https://www.ncbi.nlm.nih.gov/pubmed/29370110 http://dx.doi.org/10.3390/ijms19020360

Ejemplares similares

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
por: Chen, Q, et al.
Publicado: (2016)

Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoblasts and Adipocytes and its Role in Treatment of Osteoporosis
por: Wang, Cheng, et al.
Publicado: (2016)

MicroRNAs and long noncoding RNAs: new regulators in cell fate determination of mesenchymal stem cells
por: Wu, Zixiang, et al.
Publicado: (2019)

Scara3 regulates bone marrow mesenchymal stem cell fate switch between osteoblasts and adipocytes by promoting Foxo1
por: Chen, Peng, et al.
Publicado: (2021)

Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes
por: Xu, Xiaoyuan, et al.
Publicado: (2017)

Gene amplification in mesenchymal stem cells and during differentiation towards adipocytes or osteoblasts
por: Altmayer, Nora Corinna, et al.
Publicado: (2017)

Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiation
por: Chiellini, Chiara, et al.
Publicado: (2008)

Curcumin increases rat mesenchymal stem cell osteoblast differentiation but inhibits adipocyte differentiation
por: Gu, Qiaoli, et al.
Publicado: (2012)

Alterations in chromatin accessibility during osteoblast and adipocyte differentiation in human mesenchymal stem cells
por: Liu, Jianyun, et al.
Publicado: (2022)

Sr-substituted bone cements direct mesenchymal stem cells, osteoblasts and osteoclasts fate
por: Montesi, Monica, et al.
Publicado: (2017)

Marrow adipocytes inhibit the differentiation of mesenchymal stem cells into osteoblasts via suppressing BMP-signaling
por: Abdallah, Basem M.
Publicado: (2017)

Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes
por: Hou, Jiying, et al.
Publicado: (2022)

A biological study establishing the endotoxin limit for osteoblast and adipocyte differentiation of human mesenchymal stem cells
por: Nomura, Yusuke, et al.
Publicado: (2018)

The circadian clock has roles in mesenchymal stem cell fate decision
por: Gao, Wenzhen, et al.
Publicado: (2022)

Andrographis paniculata ameliorates estrogen deficiency-related osteoporosis by directing bone marrow mesenchymal stem cell fate
por: Song, Qian, et al.
Publicado: (2023)

Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Mesenchymal Progenitors Into Adipocytes and Osteoblasts
por: Diaz-Hernandez, Martha Elena, et al.
Publicado: (2023)

The BMP signaling pathway enhances the osteoblastic differentiation of bone marrow mesenchymal stem cells in rats with osteoporosis
por: Zhao, Bin, et al.
Publicado: (2019)

Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells
por: Qadir, Abdul, et al.
Publicado: (2020)

Complex toxicity as disruption of adipocyte or osteoblast differentiation in human mesenchymal stem cells under the mixed condition of TBBPA and TCDD
por: Kakutani, Hideki, et al.
Publicado: (2018)

Regulation of CXCR6 Expression on Adipocytes and Osteoblasts Differentiated from Human Adipose Tissue-Derived Mesenchymal Stem Cells
por: Lee, Seung-Cheol, et al.
Publicado: (2020)

The Life and Fate of Mesenchymal Stem Cells
por: Eggenhofer, Elke, et al.
Publicado: (2014)

Cell-fate decision of mesenchymal stem cells toward osteocyte differentiation is committed by spheroid culture
por: Kim, Jeonghyun, et al.
Publicado: (2021)

MicroRNA‐130a controls bone marrow mesenchymal stem cell differentiation towards the osteoblastic and adipogenic fate
por: Lin, Zhangyuan, et al.
Publicado: (2019)

Identification of a stem cell mediating osteoblast versus adipocyte lineage selection
por: Greenblatt, Matthew, et al.
Publicado: (2023)

Stiffness-mediated mesenchymal stem cell fate decision in 3D-bioprinted hydrogels
por: Liu, Yufan, et al.
Publicado: (2020)

Mesothelial cell differentiation into osteoblast- and adipocyte-like cells
por: Lansley, Sally M, et al.
Publicado: (2011)

MACF1 alleviates aging‐related osteoporosis via HES1
por: Yin, Chong, et al.
Publicado: (2021)

Knockdown of microtubule actin crosslinking factor 1 inhibits cell proliferation in MC3T3-E1 osteoblastic cells
por: Hu, Lifang, et al.
Publicado: (2015)

miR-23a/b regulates the balance between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells
por: Guo, Qi, et al.
Publicado: (2016)

Individual fates of mesenchymal stem cells in vitro
por: Krinner, Axel, et al.
Publicado: (2010)

Evidence based anti-osteoporosis effects of Periplaneta americana L on osteoblasts, osteoclasts, vascular endothelial cells and bone marrow derived mesenchymal stem cells
por: Huang, Yan-Fen, et al.
Publicado: (2017)

Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation
por: Jiang, Shanfeng, et al.
Publicado: (2022)

β-Catenin Directly Sequesters Adipocytic and Insulin Sensitizing Activities but Not Osteoblastic Activity of PPARγ2 in Marrow Mesenchymal Stem Cells
por: Rahman, Sima, et al.
Publicado: (2012)

TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes
por: Yu, Libo, et al.
Publicado: (2021)

A Subset of Osteoblasts Expressing High Endogenous Levels of PPARγ Switches Fate to Adipocytes in the Rat Calvaria Cell Culture Model
por: Yoshiko, Yuji, et al.
Publicado: (2010)

Linking cell cycle to hematopoietic stem cell fate decisions
por: Treichel, Sydney, et al.
Publicado: (2023)

Mesenchymal stem cells under epigenetic control – the role of epigenetic machinery in fate decision and functional properties
por: Walewska, Alicja, et al.
Publicado: (2023)

Effect of Glucagon-like Peptide-1 on the Differentiation of Adipose-derived Stem Cells into Osteoblasts and Adipocytes
por: Lee, Hye Min, et al.
Publicado: (2015)

Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells
por: Kokabu, Shoichiro, et al.
Publicado: (2016)

Mettl3-mediated m(6)A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis
por: Wu, Yunshu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_n7qp1tubadjkmsqm2336k56vj8